What symptom may indicate a cat has been infected with Platynosomum fastosum?

Infection by Platynosomum fastosum, commonly known as the "lizard poisoning fluke," primarily affects the liver and gallbladder of cats. One of the hallmark symptoms of this parasitic infection is cholestasis, which refers to a reduction or complete stoppage of bile flow. When bile cannot flow properly due to blockage or dysfunction, it leads to a buildup of bile acids in the liver and promotes further liver damage. This condition is often accompanied by other clinical signs such as jaundice (yellowing of the eyes, skin, and mucous membranes), vomiting, and abdominal pain.

While diarrhea, vomiting, and hair loss may occur due to other conditions in cats or may even be associated with gastrointestinal distress, they are not specific indicators tied directly to Platynosomum fastosum infection. The primary and more significant impact of this fluke is its effect on the liver and bile duct system, making cholestasis the most relevant and telling symptom of this particular infection.