Which treatment is considered ineffective for clinical coccidiosis in cattle?

Monensin is considered ineffective for the treatment of clinical coccidiosis in cattle because it is primarily used as an antibiotic and growth promoter in ruminants, rather than as an anti-coccidial medication. Though it can have some effects on coccidia due to its ionophore activity, it does not exhibit the direct coccidiocidal effects needed to effectively treat established coccidial infections.

In contrast, Amprolium, Sulfadimethoxine, and Decoquinate are all specifically formulated to target coccidia in cattle. Amprolium works by blocking thiamine metabolism in the parasite, effectively reducing its ability to thrive. Sulfadimethoxine, anti-parasitic in nature, also inhibits the growth of the coccidia. Decoquinate interferes with the energy metabolism of the coccidia. Each of these treatments is specifically designed to manage and overcome coccidial infections, making them effective choices for clinical coccidiosis in cattle.